/* ==========================================================================
   Article Page Styles - Medical Journal Style

   Design Concept: 医学誌スタイル
   - MediumやNoteのような読みやすさ
   - 医学論文のような清潔感・信頼感
   ========================================================================== */

/* CSS Variables for Article */
:root {
  --article-max-width: 760px;
  --article-font-family: -apple-system, BlinkMacSystemFont, "Helvetica Neue", "Hiragino Kaku Gothic ProN", "Yu Gothic", sans-serif;
  --article-text-color: #333333;
  --article-heading-color: #1a1a1a;
  --article-accent-color: #007AFF;
  --article-bg: #F9F9F9;
  --article-card-bg: #FFFFFF;
}

/* Article Layout
   ========================================================================== */
.article {
  min-height: 100vh;
  background: var(--article-bg);
}

.article__header {
  padding: var(--spacing-12) 0 var(--spacing-12);
  background: var(--article-card-bg);
  border-bottom: 1px solid var(--color-gray-200);
  position: relative;
  text-align: center;
  margin-bottom: 60px;
}

@media (min-width: 1280px) {
  .article__header {
    text-align: left;
  }
}

.article__header::before {
  content: '';
  position: absolute;
  top: 0;
  left: 0;
  right: 0;
  height: 3px;
  background: var(--article-accent-color);
}

.article__header .container {
  max-width: 1200px;
  padding: 0 var(--spacing-8);
}

@media (min-width: 1280px) {
  .article__header .container {
    /* Match the article body grid: 240px TOC + 48px gap = 288px offset */
    padding-left: calc(240px + var(--spacing-12) + var(--spacing-8));
  }
}

/* Breadcrumb - Subtle navigation */
.article__breadcrumb {
  display: flex;
  align-items: center;
  justify-content: center;
  flex-wrap: wrap;
  gap: var(--spacing-3);
  font-size: 13px;
  color: var(--color-gray-500);
  margin-bottom: var(--spacing-8);
  letter-spacing: 0.02em;
}

@media (min-width: 1280px) {
  .article__breadcrumb {
    justify-content: flex-start;
  }
}

.article__breadcrumb a {
  color: var(--color-gray-500);
  text-decoration: none;
  transition: color 0.2s ease;
}

.article__breadcrumb a:hover {
  color: var(--article-accent-color);
}

.article__breadcrumb-separator {
  color: var(--color-gray-400);
  margin: 0 2px;
}

.article__breadcrumb-current {
  color: var(--color-gray-700);
  font-weight: 500;
  overflow: hidden;
  text-overflow: ellipsis;
  white-space: nowrap;
  max-width: 300px;
}

.article__back {
  display: inline-flex;
  align-items: center;
  gap: var(--spacing-2);
  color: var(--color-gray-600);
  text-decoration: none;
  font-size: var(--font-size-sm);
  margin-bottom: var(--spacing-6);
  transition: all 0.2s ease;
  padding: var(--spacing-2) var(--spacing-3);
  border-radius: var(--radius-md);
}

.article__back:hover {
  color: var(--article-accent-color);
  background: var(--color-gray-100);
}

.article__meta {
  display: flex;
  align-items: center;
  justify-content: center;
  gap: 15px;
  margin-bottom: 20px;
}

@media (min-width: 1280px) {
  .article__meta {
    justify-content: flex-start;
  }
}

.article__category {
  display: inline-block;
  padding: 6px 16px;
  background: #EBF5FF;
  color: var(--article-accent-color);
  font-size: var(--font-size-sm);
  font-weight: 600;
  border-radius: 20px;
  letter-spacing: 0.02em;
}

.article__date {
  font-size: var(--font-size-sm);
  color: var(--color-gray-500);
}

.article__title {
  font-family: var(--article-font-family);
  font-size: clamp(1.75rem, 4vw, 2.25rem);
  font-weight: 700;
  line-height: 1.4;
  color: var(--article-heading-color);
  margin-bottom: 32px;
  letter-spacing: -0.02em;
  max-width: none;
}

.article__excerpt {
  font-family: var(--article-font-family);
  font-size: var(--font-size-base);
  color: var(--color-gray-600);
  line-height: 1.8;
  max-width: 640px;
  margin-left: auto;
  margin-right: auto;
}

/* Abstract Box (要旨) */
.article__abstract {
  background: #F5F7FA;
  padding: 30px 32px;
  border-radius: 0 8px 8px 0;
  border-left: 5px solid var(--article-accent-color);
  margin-top: 0;
  margin-bottom: 0;
  max-width: none;
  text-align: left;
  box-shadow: 0 2px 8px rgba(0, 0, 0, 0.04);
}

.article__abstract-title {
  font-family: var(--article-font-family);
  font-size: var(--font-size-sm);
  font-weight: 700;
  text-transform: uppercase;
  letter-spacing: 0.1em;
  color: var(--article-accent-color);
  margin-bottom: var(--spacing-3);
}

.article__abstract-text {
  font-size: 15px;
  line-height: 1.9;
  color: var(--color-gray-700);
}

/* Reading Time */
.article__reading-time {
  display: inline-flex;
  align-items: center;
  gap: 6px;
  font-size: var(--font-size-sm);
  color: var(--color-gray-500);
}

.article__reading-time svg {
  width: 16px;
  height: 16px;
}

/* Article Body
   ========================================================================== */
.article__body {
  padding: var(--spacing-10) 0 var(--spacing-16);
}

.container--article {
  max-width: calc(var(--article-max-width) + var(--spacing-8));
  margin: 0 auto;
  padding: 0 var(--spacing-4);
  display: block;
}

@media (min-width: 1280px) {
  .container--article {
    max-width: 1200px;
    display: grid;
    grid-template-columns: 240px 1fr;
    gap: var(--spacing-12);
    padding: 0 var(--spacing-8);
  }
}

/* Article Content Wrapper - Card Style */
.article__content-wrapper {
  background: var(--article-card-bg);
  border-radius: var(--radius-lg);
  box-shadow: 0 1px 3px rgba(0, 0, 0, 0.08), 0 4px 12px rgba(0, 0, 0, 0.04);
  padding: var(--spacing-8) var(--spacing-6);
}

@media (min-width: 768px) {
  .article__content-wrapper {
    padding: var(--spacing-12) var(--spacing-10);
  }
}

@media (min-width: 1280px) {
  .article__content-wrapper {
    padding: var(--spacing-12);
  }
}

/* Table of Contents - Desktop Sticky Sidebar
   ========================================================================== */
.article__toc {
  display: none;
}

@media (min-width: 1280px) {
  .article__toc {
    display: block;
    position: sticky;
    top: calc(var(--header-height, 80px) + var(--spacing-6));
    align-self: start;
    max-height: calc(100vh - var(--header-height, 80px) - var(--spacing-12));
    overflow-y: auto;
    padding-right: var(--spacing-4);
    padding-bottom: var(--spacing-8);
  }
}

.article__toc-title {
  font-family: var(--article-font-family);
  font-size: var(--font-size-xs);
  font-weight: 700;
  text-transform: uppercase;
  letter-spacing: 0.1em;
  color: var(--color-gray-500);
  margin-bottom: var(--spacing-4);
  padding-bottom: var(--spacing-2);
  border-bottom: 1px solid var(--color-gray-200);
}

.article__toc-list {
  list-style: none;
  padding: 0;
  margin: 0;
}

.article__toc-item {
  margin-bottom: var(--spacing-1);
}

.article__toc-item--h3 {
  padding-left: var(--spacing-3);
}

.article__toc-link {
  display: block;
  padding: var(--spacing-2) var(--spacing-3);
  font-family: var(--article-font-family);
  font-size: 13px;
  color: var(--color-gray-600);
  text-decoration: none;
  border-radius: var(--radius-sm);
  transition: all 0.2s ease;
  line-height: 1.5;
  border-left: 2px solid transparent;
}

.article__toc-link:hover {
  color: var(--article-accent-color);
  background: var(--color-gray-50);
}

.article__toc-link.is-active {
  color: var(--article-accent-color);
  background: rgba(0, 122, 255, 0.06);
  border-left-color: var(--article-accent-color);
  font-weight: 600;
}

/* Mobile TOC - Accordion
   ========================================================================== */
.article__toc-mobile {
  display: block;
  margin-bottom: var(--spacing-8);
  background: var(--color-gray-50);
  border-radius: var(--radius-md);
  border: 1px solid var(--color-gray-200);
}

@media (min-width: 1280px) {
  .article__toc-mobile {
    display: none;
  }
}

.article__toc-toggle {
  width: 100%;
  display: flex;
  align-items: center;
  justify-content: space-between;
  padding: var(--spacing-4);
  background: none;
  border: none;
  cursor: pointer;
  font-family: var(--article-font-family);
  font-size: var(--font-size-sm);
  font-weight: 600;
  color: var(--color-gray-700);
}

.article__toc-toggle-icon {
  width: 20px;
  height: 20px;
  transition: transform 0.2s ease;
}

.article__toc-mobile.is-open .article__toc-toggle-icon {
  transform: rotate(180deg);
}

.article__toc-mobile-content {
  display: none;
  padding: 0 var(--spacing-4) var(--spacing-4);
}

.article__toc-mobile.is-open .article__toc-mobile-content {
  display: block;
}

.article__toc-mobile .article__toc-list {
  max-height: 300px;
  overflow-y: auto;
}

/* Loading State
   ========================================================================== */
.article__loading {
  display: flex;
  flex-direction: column;
  align-items: center;
  justify-content: center;
  padding: var(--spacing-16) 0;
  color: var(--color-gray-500);
}

.article__loading-spinner {
  width: 40px;
  height: 40px;
  border: 3px solid var(--color-gray-200);
  border-top-color: var(--article-accent-color);
  border-radius: 50%;
  animation: spin 1s linear infinite;
  margin-bottom: var(--spacing-4);
}

@keyframes spin {
  to {
    transform: rotate(360deg);
  }
}

.article__error {
  text-align: center;
  color: var(--color-gray-600);
}

.article__error a {
  color: var(--article-accent-color);
}

/* ==========================================================================
   Markdown Body Styles - Medical Journal Typography
   ========================================================================== */
.markdown-body {
  font-family: var(--article-font-family);
  font-size: 17px;
  line-height: 2.0;
  color: var(--article-text-color);
  max-width: var(--article-max-width);
  margin: 0 auto;
}

/* Headings */
.markdown-body h1,
.markdown-body h2,
.markdown-body h3,
.markdown-body h4,
.markdown-body h5,
.markdown-body h6 {
  font-family: var(--article-font-family);
  font-weight: 700;
  line-height: 1.4;
  color: var(--article-heading-color);
  scroll-margin-top: calc(var(--header-height, 80px) + var(--spacing-4));
}

.markdown-body h1 {
  font-size: 1.75rem;
  margin-top: var(--spacing-8);
  margin-bottom: var(--spacing-6);
  padding-bottom: var(--spacing-4);
  border-bottom: 2px solid var(--color-gray-200);
}

.markdown-body h2 {
  font-size: 1.625rem;
  margin-top: 80px;
  margin-bottom: 30px;
  padding-top: 0;
  padding-bottom: var(--spacing-4);
  border-bottom: 2px solid #E0E0E0;
}

.markdown-body h3 {
  font-size: 1.375rem;
  margin-top: var(--spacing-12);
  margin-bottom: var(--spacing-5);
  padding-left: 15px;
  border-left: 5px solid var(--article-accent-color);
}

.markdown-body h4 {
  font-size: 1.1rem;
  color: var(--color-gray-700);
  margin-top: var(--spacing-8);
  margin-bottom: var(--spacing-3);
}

/* First heading after main image */
.markdown-body > figure:first-child + h2,
.markdown-body > h2:first-child {
  margin-top: var(--spacing-6);
}

/* Paragraphs */
.markdown-body p {
  margin-bottom: 2em;
  line-height: 2.0;
}

/* Lead paragraph (first paragraph after h2) */
.markdown-body h2 + p {
  font-size: 1.05em;
  color: var(--color-gray-600);
  line-height: 2.0;
}

/* Links */
.markdown-body a {
  color: var(--article-accent-color);
  text-decoration: underline;
  text-underline-offset: 2px;
  transition: opacity 0.2s ease;
}

.markdown-body a:hover {
  opacity: 0.8;
}

/* Lists */
.markdown-body ul,
.markdown-body ol {
  margin-bottom: var(--spacing-6);
  padding-left: var(--spacing-6);
}

.markdown-body ul {
  list-style: disc;
}

.markdown-body ul li {
  margin-bottom: var(--spacing-2);
  padding-left: var(--spacing-1);
}

.markdown-body ul li::marker {
  color: var(--article-accent-color);
}

/* Nested lists */
.markdown-body ul ul,
.markdown-body ol ol {
  margin-top: var(--spacing-2);
  margin-bottom: var(--spacing-2);
}

.markdown-body ul ul {
  list-style: circle;
}

.markdown-body ol {
  list-style: decimal;
}

.markdown-body ol li {
  margin-bottom: var(--spacing-2);
  padding-left: var(--spacing-1);
}

.markdown-body ol li::marker {
  color: var(--article-accent-color);
  font-weight: 600;
}

.markdown-body li > p {
  margin-bottom: var(--spacing-2);
}

/* Blockquotes - Medical Journal Callout Style */
.markdown-body blockquote {
  margin: 30px 0;
  padding: 16px 20px;
  border-left: 4px solid var(--article-accent-color);
  background: #F2F7FF;
  border-radius: 0 var(--radius-md) var(--radius-md) 0;
  color: #555555;
}

.markdown-body blockquote p {
  margin-bottom: var(--spacing-3);
}

.markdown-body blockquote p:last-child {
  margin-bottom: 0;
}

.markdown-body blockquote strong {
  color: var(--article-heading-color);
}

/* Pull Quote - 強調引用 */
.markdown-body .pull-quote,
.markdown-body blockquote.pull-quote {
  margin: 48px 0;
  padding: 0;
  border: none;
  background: transparent;
  text-align: center;
  position: relative;
}

.markdown-body .pull-quote p,
.markdown-body blockquote.pull-quote p {
  font-size: 1.375rem;
  font-weight: 600;
  line-height: 1.6;
  color: var(--article-heading-color);
  margin-bottom: 0;
}

.markdown-body .pull-quote::before {
  content: '"';
  display: block;
  font-size: 4rem;
  line-height: 1;
  color: var(--article-accent-color);
  opacity: 0.3;
  margin-bottom: -16px;
}

/* Code */
.markdown-body code {
  font-family: 'SF Mono', Consolas, 'Liberation Mono', Menlo, monospace;
  font-size: 0.875em;
  padding: 0.2em 0.5em;
  background: var(--color-gray-100);
  border-radius: var(--radius-sm);
  color: #d63384;
}

.markdown-body pre {
  margin: var(--spacing-6) 0;
  padding: var(--spacing-5);
  background: #1e293b;
  border-radius: var(--radius-md);
  overflow-x: auto;
}

.markdown-body pre code {
  padding: 0;
  background: transparent;
  color: #e2e8f0;
  font-size: var(--font-size-sm);
}

/* Tables - Medical Journal Style */
.article__table-wrapper {
  margin: var(--spacing-8) 0;
  overflow-x: auto;
  -webkit-overflow-scrolling: touch;
}

.article__table {
  width: 100%;
  border-collapse: collapse;
  font-size: 15px;
}

.article__table th,
.article__table td {
  padding: var(--spacing-3) var(--spacing-4);
  text-align: left;
  border-bottom: 1px solid var(--color-gray-200);
}

.article__table th {
  background: var(--color-gray-100);
  font-weight: 600;
  color: var(--article-heading-color);
  white-space: nowrap;
  font-size: 14px;
}

.article__table tbody tr:hover {
  background: var(--color-gray-50);
}

/* Images */
.article__figure {
  margin: 40px 0;
  padding: 0;
}

.article__image {
  width: 100%;
  height: auto;
  border-radius: 8px;
  border: 1px solid var(--color-gray-200);
  box-shadow: 0 4px 16px rgba(0, 0, 0, 0.08);
}

.article__figcaption {
  margin-top: var(--spacing-4);
  padding-top: var(--spacing-3);
  font-size: 13px;
  color: var(--color-gray-500);
  text-align: center;
  line-height: 1.6;
  border-top: 1px solid var(--color-gray-100);
}

.article__figcaption::before {
  content: '図';
  font-weight: 600;
  color: var(--article-accent-color);
  margin-right: 4px;
}

/* Horizontal Rule */
.markdown-body hr {
  margin: var(--spacing-12) 0;
  border: none;
  border-top: 1px solid var(--color-gray-200);
}

/* Strong / Bold */
.markdown-body strong {
  font-weight: 700;
  color: var(--article-heading-color);
}

/* Emphasis / Italic */
.markdown-body em {
  font-style: italic;
}

/* Author Info Section
   ========================================================================== */
.article__author {
  margin-top: var(--spacing-12);
  padding: var(--spacing-6);
  background: var(--color-gray-50);
  border-radius: var(--radius-lg);
  border: 1px solid var(--color-gray-200);
}

.article__author-title {
  font-family: var(--article-font-family);
  font-size: var(--font-size-xs);
  font-weight: 700;
  text-transform: uppercase;
  letter-spacing: 0.1em;
  color: var(--color-gray-500);
  margin-bottom: var(--spacing-4);
}

.article__author-content {
  display: flex;
  align-items: flex-start;
  gap: var(--spacing-4);
}

.article__author-avatar {
  width: 56px;
  height: 56px;
  border-radius: 50%;
  background: var(--color-gray-300);
  display: flex;
  align-items: center;
  justify-content: center;
  flex-shrink: 0;
}

.article__author-avatar svg {
  width: 28px;
  height: 28px;
  color: var(--color-gray-500);
}

.article__author-info {
  flex: 1;
}

.article__author-name {
  font-family: var(--article-font-family);
  font-size: var(--font-size-base);
  font-weight: 600;
  color: var(--article-heading-color);
  margin-bottom: var(--spacing-1);
}

.article__author-bio {
  font-size: var(--font-size-sm);
  color: var(--color-gray-600);
  line-height: 1.6;
}

/* Article CTA Section
   ========================================================================== */
.article__cta {
  margin-top: var(--spacing-12);
  padding: var(--spacing-8);
  background: linear-gradient(135deg, #f0f7ff 0%, #e8f4fd 100%);
  border-radius: var(--radius-lg);
  text-align: center;
  border: 1px solid rgba(0, 122, 255, 0.2);
}

.article__cta-title {
  font-family: var(--article-font-family);
  font-size: var(--font-size-lg);
  font-weight: 700;
  color: var(--article-heading-color);
  margin-bottom: var(--spacing-3);
}

.article__cta-description {
  font-size: var(--font-size-sm);
  color: var(--color-gray-600);
  margin-bottom: var(--spacing-6);
  line-height: 1.7;
}

.article__cta-buttons {
  display: flex;
  flex-wrap: wrap;
  gap: var(--spacing-3);
  justify-content: center;
}

/* Article Footer Nav
   ========================================================================== */
.article__footer {
  padding: var(--spacing-8) 0;
  background: var(--article-card-bg);
  border-top: 1px solid var(--color-gray-200);
}

.article__nav {
  display: flex;
  justify-content: space-between;
  align-items: center;
  flex-wrap: wrap;
  gap: var(--spacing-4);
}

.article__nav-link {
  display: inline-flex;
  align-items: center;
  gap: var(--spacing-2);
  color: var(--color-gray-600);
  text-decoration: none;
  font-size: var(--font-size-sm);
  transition: all 0.2s ease;
  padding: var(--spacing-2) var(--spacing-3);
  border-radius: var(--radius-md);
}

.article__nav-link:hover {
  color: var(--article-accent-color);
  background: var(--color-gray-100);
}

/* Reading Progress Bar */
.article__progress {
  position: fixed;
  top: var(--header-height, 80px);
  left: 0;
  width: 100%;
  height: 3px;
  background: var(--color-gray-200);
  z-index: 100;
}

.article__progress-bar {
  height: 100%;
  background: var(--article-accent-color);
  width: 0%;
  transition: width 0.1s ease;
}

/* Responsive
   ========================================================================== */
@media (max-width: 768px) {
  .article__header {
    padding: var(--spacing-8) 0 var(--spacing-8);
    text-align: center;
    margin-bottom: 40px;
  }

  .article__breadcrumb {
    font-size: 12px;
    margin-bottom: var(--spacing-6);
    gap: var(--spacing-2);
  }

  .article__title {
    font-size: 1.5rem;
    margin-bottom: 20px;
  }

  .article__abstract {
    padding: 24px 20px;
    margin-left: var(--spacing-4);
    margin-right: var(--spacing-4);
    border-left-width: 4px;
  }

  .article__meta {
    flex-wrap: wrap;
    gap: var(--spacing-2);
  }

  .article__reading-time {
    width: 100%;
    justify-content: center;
    margin-top: var(--spacing-2);
  }

  .article__body {
    padding: var(--spacing-6) 0 var(--spacing-12);
  }

  .article__content-wrapper {
    padding: var(--spacing-6) var(--spacing-4);
    border-radius: 0;
    box-shadow: none;
    border-top: 1px solid var(--color-gray-200);
    border-bottom: 1px solid var(--color-gray-200);
  }

  .markdown-body {
    font-size: 16px;
    line-height: 1.9;
  }

  .markdown-body p {
    margin-bottom: 1.75em;
  }

  .markdown-body h2 {
    margin-top: 56px;
    margin-bottom: 24px;
    font-size: 1.375rem;
  }

  .markdown-body h3 {
    font-size: 1.125rem;
    padding-left: 12px;
    border-left-width: 4px;
  }

  .article__table-wrapper {
    margin-left: calc(var(--spacing-4) * -1);
    margin-right: calc(var(--spacing-4) * -1);
  }

  .article__figure {
    margin-left: calc(var(--spacing-4) * -1);
    margin-right: calc(var(--spacing-4) * -1);
  }

  .article__image {
    border-radius: 0;
  }

  .article__breadcrumb-current {
    max-width: 150px;
  }
}

/* PDF Download Section
   ========================================================================== */
.pdf-download-section {
  margin: var(--spacing-8) 0;
  padding: var(--spacing-6);
  background: var(--color-gray-50);
  border-radius: var(--radius-lg);
  border: 1px solid var(--color-gray-200);
}

/* Hero variant - wider and more prominent at top of article */
.pdf-download-section--hero {
  margin: var(--spacing-10) calc(var(--spacing-8) * -1);
  padding: var(--spacing-8);
  background: linear-gradient(135deg, #f8fafc 0%, #f1f5f9 100%);
  border: none;
  border-radius: var(--radius-xl);
  box-shadow: 0 4px 20px rgba(0, 0, 0, 0.08);
}

@media (min-width: 768px) {
  .pdf-download-section--hero {
    margin-left: calc(var(--spacing-12) * -1);
    margin-right: calc(var(--spacing-12) * -1);
  }
}

.pdf-preview {
  margin-bottom: var(--spacing-6);
  border-radius: var(--radius-md);
  overflow: hidden;
  box-shadow: 0 2px 8px rgba(0, 0, 0, 0.1);
}

.pdf-download-section--hero .pdf-preview {
  border-radius: var(--radius-lg);
  box-shadow: 0 8px 32px rgba(0, 0, 0, 0.12);
}

.pdf-preview embed,
.pdf-preview iframe {
  display: block;
  width: 100%;
  min-height: 500px;
  border: none;
}

.pdf-download-section--hero .pdf-preview embed,
.pdf-download-section--hero .pdf-preview iframe {
  min-height: 600px;
}

.pdf-download-link {
  text-align: center;
}

.pdf-download-link .btn {
  display: inline-flex;
  align-items: center;
  gap: var(--spacing-2);
  font-size: var(--font-size-base);
}

/* PDF fallback for mobile/unsupported browsers */
@media (max-width: 768px) {
  .pdf-preview {
    display: none;
  }

  .pdf-download-section {
    padding: var(--spacing-4);
  }
}

/* Print styles */
@media print {
  .article__toc,
  .article__toc-mobile,
  .article__progress,
  .article__back,
  .article__breadcrumb,
  .article__footer,
  .article__cta,
  .pdf-download-section {
    display: none !important;
  }

  .article__content-wrapper {
    box-shadow: none;
    padding: 0;
  }

  .markdown-body {
    font-size: 12pt;
  }
}